Individual covariate values for 100 patients used in the warfarin covariate sensitivity simulation, including demographic and pharmacogenomic variables.
Format
ds_covval
A data frame with 100 rows and 9 columns:
- ID
individual patient identifier
- AGE
age in years
- WEIGHT
body weight in kg
- BMI
body mass index (kg/m2)
- LG_WEIGHT
log-transformed body weight (log10 scale), used as continuous covariate in the PK model
- LG_AGE
log-transformed age (log10 scale), used as continuous covariate in the PK model
- SEX
sex of the individual (0 = female, 1 = male)
- CYP2C9
CYP2C9 genotype encoded as integer: 0 = *1/*1 (reference), 1 = *1/*2, 2 = *1/*3, 3 = *2/*2, 4 = *2/*3, 5 = *3/*3
- VKORC1
VKORC1 genotype (
"GG","AG", or"AA")