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Bundled GMO: one-compartment oral PK model with inter-individual variability on ka, Vd, and CL, linear covariate effect of WT on Vd (beta_Vd_WT), and proportional residual error on Cc_ResErr.

Usage

gmo_pk1c

Format

gmo_pk1c

An rxode2 model object with population parameters (*_pop), random-effect placeholders (omega_*), covariate effect beta_Vd_WT, structural ODEs (Ad, Ac, Cc), and residual error output (Cc_ResErr).