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Final parameter estimates from a warfarin population pharmacokinetic model, including typical values, covariate effects, random effects, and residual error parameters with associated uncertainty measures.

Usage

parest

Format

parest

A data frame with 15 rows and 12 columns:

parameter

parameter name as used in the model

value

final parameter estimate

TYPE

parameter category:"Typical values", "Covariate effects", "Random effects", or "Residual error model"

EST

estimation status ("ESTIMATED")

SE

standard error of the estimate

RSE

relative standard error (%)

LCI

lower bound of the 95 % confidence interval

UCI

upper bound of the 95 % confidence interval

ETAshrinkage_var

ETA shrinkage on the variance scale (%); NA for non-random-effect parameters

ETAshrinkage_sd

ETA shrinkage on the SD scale (%); NA for non-random-effect parameters

EPSshrinkage_sd

EPS shrinkage on the SD scale (%); NA for non-residual-error parameters

Source

Derived from par_fin_i.csv — warfarin PopPK model estimation output.